Local steroids and dysphagia in anterior cervical discectomy and fusion-does the employment of rhBMP-2 make their use a necessity?
نویسندگان
چکیده
Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, USA; Department of Neurosurgery, Buffalo General Medical Center, Department of Neurosurgery, School of Medicine, University of Thessaly, Larisa, Greece Correspondence to: Ioannis D. Siasios, MD, MSc. University at Buffalo Neurosurgery, 100 High Street, Suite B4, Buffalo, NY 14209, USA. Email: [email protected].
منابع مشابه
Can Dysphagia Following Anterior Cervical Fusions With rhBMP-2 Be Reduced With Local Depomedrol Application?: A Prospective, Randomized, Placebo-Controlled, Double-Blind Trial.
STUDY DESIGN A prospective, randomized, placebo-controlled, double-blind trial. OBJECTIVE The aim of this study was to investigate whether the local administration of depomedrol decreases the severity of dysphagia after anterior cervical discectomy and fusion (ACDF) surgery using bone morphogenetic protein (BMP). SUMMARY OF BACKGROUND DATA Although recombinant human BMP-2 is effective in pr...
متن کاملComparison of outcomes and safety of using hydroxyapatite granules as a substitute for autograft in cervical cages for anterior cervical discectomy and interbody fusion
Background: After cervical discectomy, autogenetic bone is packed into the cage to increase the rate of union between adjacent vertebral bodies, but donor site–related complications can still occur. In this study we evaluate the use of hydroxyapatite granules as a substitute for autograft for interbody fusion. Methods: From November 2008 to November 2011, 236 patients participated in ...
متن کاملComplications of Anterior Cervical Fusion using a Low-dose Recombinant Human Bone Morphogenetic Protein-2
OBJECTIVE There are several reports, which documented a high incidence of complications following the use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in anterior cervical fusions (ACFs). The objective of this study is to share our experience with low-dose rhBMP-2 in anterior cervical spine. METHODS We performed a retrospective analysis of 197 patients who underwent anterior ce...
متن کاملComparison of rhBMP-2 versus Autogenous Iliac Crest Bone Graft for 2-Level Anterior Cervical Discectomy and Fusion for Cervical Spondylotic Myelopathy
BACKGROUND Few studies have examined the efficacy of recombinant human bone morphogenetic protein-2 (rhBMP-2) in 2-level anterior cervical discectomy and fusion (ACDF). The purpose of this study was to compare the outcomes in a series of patients with CSM treated with 2-level ACDF with or without rhBMP-2. MATERIAL AND METHODS The retrospective study included a total of 146 patients with CSM. ...
متن کاملAdverse swelling associated with use of rh-BMP-2 in anterior cervical discectomy and fusion.
BACKGROUND CONTEXT The use of recombinant bone morphogenetic protein-2 (rh-BMP-2) is effective in augmenting lumbar spinal fusions. A safe, effective dosage of rh-BMP-2 in the cervical spine has yet to be determined. Use of rh-BMP-2 is currently being evaluated and is only indicated for use in the cervical spine on Investigational Device Exempt cases. PURPOSE To present a potentially serious ...
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ورودعنوان ژورنال:
- Journal of spine surgery
دوره 2 3 شماره
صفحات -
تاریخ انتشار 2016